Development of cephalexin-loaded poly(ethyl cyanoacrylate) colloidal nanospheres

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Discriminatory Dissolution Method Development and Validation for Cephalexin Od Tablets

In this study, a discriminative dissolution method was developed for Cephalexin OD (orally disintegrating) tablets 750mg. The solubility and stability of the cephalexin API was determined in ten different solutions. In that 0.01N HCl, glycine buffer pH 3-0, acetate buffer pH 4.5 and water gave good stability and the solubility. Dissolution profiling of cephalexin OD tablets 750mg of single batc...

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ژورنال

عنوان ژورنال: Open Chemistry

سال: 2012

ISSN: 2391-5420

DOI: 10.2478/s11532-011-0143-2